Global skin action of a laminaria extract / Alain Thibodeau in PERSONAL CARE EUROPE, Vol. 8, N° 3 (04/2015)  

[article]  inPERSONAL CARE EUROPE > Vol. 8, N° 3 (04/2015) . - p. 53-56 Titre : Global skin action of a laminaria extract Type de document : texte imprimé Auteurs : Alain Thibodeau, Auteur Année de publication : 2015 Article en page(s) : p. 53-56 Langues : Anglais (eng) Catégories : Algues marines Antiâge:Antirides Cosmétiques Extraits de plantes:Extraits (pharmacie) Ingrédients cosmétiques Laminaires La Laminaire (Laminaria) est un genre d'algues brunes de la famille des Laminariaceae. Son thalle en forme de ruban peut mesurer jusqu'à 4 m de long. Certaines laminaires sont récoltées de manière artisanale ou industrielle. Elles étaient utilisées au même titre que le (goémon) comme engrais, puis dans l'industrie agroalimentaire pour leurs polysaccharides ; les alginates qui sont des gélifiants alimentaires. Reconnaissable par les codes E400 à E405, les alginates forment des gels thermostables (qui ne se liquéfient pas à la chaleur) qui permettent la tenue, la reconstruction des aliments (jambon, poisson pané). Peau -- Soins et hygiène Index. décimale : 668.5 Parfums et cosmétiques Résumé : Skin is a large and complex tissue where the orchestral actions of resident cells are necessary to support its structural and metabolic integrity. Cells of the epidermis ( mainly keratinocytes ) play a role in protecting from environmental stress such as UV exposure, mechanical damage and pro-oxidative attacks. Perhaps more importantly, top layers of the epidermis along with a lipid-rich intercellular matrix from the skin barrier. It is no secret that the skin barrier is fundamental in preventing excessive water evaporation thereby supporting normal skin hydratation levels. A functional barrier also prevents penetration of allergens that sometimes can exacerbate sensitive skin conditions. With age, the rate of epidermal cell renewal and the ability of the skin barrier to repair from a physical insult decrease. Ageing not only weakens epidermal structures and functions but also deregulates the metabolic activity of fibroblasts. Indeed, some metabolic pathways are increased and others are decreased in aged skin fibroblasts. The best example is the general reduction in collagen synthesis and the augmentation in the production of matrix metalloproteases (MMPs) causing a gradual dismantling of the extracellular matrix (ECM) organisation. We tested a laminaria extract ( commercial name : Regenesea-LS, INCI Name : Glycerin (and) Water (and) Laminaria saccharina extract ) for its effects on epîdermal molecular pathways using cDNA experiments on human skin equivalents. We also verified the ability of the laminaria extract in rejuvenating aged skin fibroblasts at the gene expression level. The actions of the extract were confirmed clinically by measuring various parameters including skin barrier function, hydratation, skin smoothness, wrinkle density and volume as well as visco-elastic properties. Note de contenu : - Fig. 1 : Epidermal site of expression/function of various gene/proteins - Table 1 : Effect of the laminaria extract on the expression of epidermal constituents - Fig. 2 : Metabolic pathways regulated upon ageing and rejuvenated in the presence of the laminaria extract - Table 2 : Clinical benefits of the laminaria extract based on epidermal actions - Table 3 : Gene expression profile during ageing and effects of laminaria - Fig. 3 : Proposed anti-wrinkle mechanisms of action of the laminaria extract - Table 4 : Clinical benefits of the laminaria extract based on aged fibroblast metabolism rejuvenations En ligne : https://drive.google.com/file/d/1vawhIA2AP5ZMkgekrKOVTaqzXpQGbBLe/view?usp=drive [...] Format de la ressource électronique : Pdf Permalink : https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=23697 [article]

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