[article]
Titre : |
Anti-wrinkle therapy : significant new findings in the non-invasive cosmetic treatment of skin wrinkles with beta-glucan |
Type de document : |
document électronique |
Auteurs : |
Ravi Pillai, Auteur ; M. Redmond, Auteur ; J. Röding, Auteur |
Année de publication : |
2005 |
Article en page(s) : |
p. 17-21 |
Note générale : |
Bibliogr. |
Langues : |
Anglais (eng) |
Catégories : |
Absorption cutanée Antiâge:Antirides Cosmétiques GlucanesUn glucane est un polysaccharide (polymère d'oses) composé exclusivement de monomère de glucose. Ils peuvent être linéaires ou bien ramifiés.
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Index. décimale : |
668.5 Parfums et cosmétiques |
Résumé : |
Oat beta-glucan is a water soluble, linear polymer of glucose consisting of 1,4 (70%) and 1,3 (30%) linkages with an average molecular weight of 1 × 106 Da. Scientific reports indicate beta-glucan is a film-forming moisturizer, a biological response modifier, and a promoter of wound healing. Our objective was to study the penetration of oat (1,4:1,3) beta-glucan in human skin models and to evaluate clinically its efficacy for reducing fine-lines and wrinkles. Penetration studies performed on human abdominal skin used a single application of 0.5% beta-glucan solution at a dose of 5 mg per cm2. The results showed that beta-glucan, despite its large molecular size, deeply penetrated the skin into the epidermis and dermis. A clinical study of 27 subjects was performed to evaluate the effects of beta-glucan on facial fine-lines and wrinkles. After 8 weeks of treatment, digital image analysis of silicone replicas indicated a significant reduction of wrinkle depth and height, and overall roughness.
This work is the first ex vivo and in vivo demonstration of the physiological effects of beta-glucan in the penetration and restructuring of human tissue. The study supports the use of oat beta-glucan in the care and maintenance of healthy skin and the cosmetic treatment of the signs of aging. |
Permalink : |
https://e-campus.itech.fr/pmb/opac_css/index.php?lvl=notice_display&id=10463 |
in IFSCC MAGAZINE > Vol. 8, N° 1 (01-02-03/2005) . - p. 17-21
[article]
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